Official Journal of the Human Genome Organisation
Table 1 Anthropometric and clinical characteristics of the study groups
Characteristics | Control subjects | Type 2 diabetic patients | P value |
|---|---|---|---|
N (men/women) | 812 (427/385) | 1,040 (577/463) | |
Age (years) | 50 (45–61) | 54 (45–63) | 0.004 |
BMI (kg/m2) | |||
Men | 23.1 (19.5–25.6) | 23.8 (23.0–25.8) | 3.6 × 10−6 |
Women | 24.8 (20.8–28.3) | 26.7 (24.2–29.4) | 9.0 × 10−10 |
WHR | |||
Men | 0.95 (0.90–0.98) | 1.0 (0.97–1.03) | 1.2 × 10−26 |
Women | 0.86 (0.82–0.92) | 1.0 (0.97–1.03) | 6.7 × 10−5 |
Systolic BP (mmHg) | 124 (114–136) | 130 (130–140) | 3.8 × 10−24 |
Diastolic BP (mmHg) | 80 (70–86) | 80 (76–87) | 4.9 × 10−6 |
HbA1c (%) | 5.3 (4.9–5.6) | 7.7 (6.5–9.2) | 1.9 × 10−221 |
Fasting glucose (mmoles/l) | 4.9 (4.4–5.3) | 7.7 (6.3–10.0) | 2.2 × 10−203 |
hsCRP (mg/l) | 1.2 (0.6–2.8) | 2.1 (0.9–4.4) | 4.8 × 10−14 |
Total cholesterol (mg/dl) | 172 (147–201) | 165 (139–195) | 0.004 |
LDL-C (mg/dl) | 109 (91–134) | 101 (80–129) | 1.8 × 10−5 |
HDL-C (mg/dl) | 43 (35–51) | 42 (36–48) | 0.153 |
Triglycerides (mg/dl) | 116 (86–159) | 137 (96–196) | 4.3 × 10−8 |
Urea (mg/dl) | 24.1 (19.2–29.2) | 27.0 (20.9–34.3) | 1.2 × 10−9 |
Uric acid (mg/dl) | 4.7 (3.8–5.6) | 4.9 (3.9–6.0) | 0.033 |
Creatinine (mg/dl) | 0.74 (0.65–0.88) | 0.90 (0.72–1.10) | 6.4 × 10−28 |