Table 3 Allelic and genotypic distribution of TNFRSF1B polymorphisms among normal-weight and over-weight/obese individuals in North Indian population

(CA) _n

Allele

2n = 712

2n = 568

2n = 894

2n = 1,448

(CA)₁₁

43 (6.1)

50 (8.8)

52 (5.8)

97 (6.7)

(CA)₁₂

6 (0.8)

7 (1.2)

8 (0.9)

16 (1.1)

(CA)₁₃

126 (17.7)

111 (19.5)

174 (19.5)

270 (18.6)

(CA)₁₄

14 (2.0)

9 (1.6)

25 (2.8)

31 (2.1)

(CA)₁₅

398 (55.9)

309 (54.4)

479 (53.6)

789 (54.5)

(CA)₁₆

122 (17.1)

76 (13.4)

145 (16.2)

228 (15.8)

(CA)₁₇

3 (0.4)

6 (1.1)

11 (1.2)

17 (1.2)

OR (95% CI)*

0.94 (0.75–1.17)

1.04 (0.88–1.23)

P value

0.63

0.70

rs1061622

MAF, G

26.5

28.8

26.4

26.0

Genotype

n = 356

n = 283

n = 447

n = 713

GG

21 (5.9)

26 (9.2)

25 (5.6)

48 (6.7)

GT

147 (41.3)

111 (39.2)

168 (37.6)

288 (40.4)

TT

188 (52.8)

146 (51.6)

254 (56.8)

377 (52.9)

OR (95% CI)**

1.05 (0.77–1.43)

1.17 (0.92–1.49)

P value

0.82

0.21

rs3397

MAF, T

39.9

42.9

44.4

40.4

Genotype

n = 356

n = 282

n = 447

n = 718

TT

50 (14.0)

51 (18.1)

87 (19.5)

106 (14.8)

CT

184 (51.7)

140 (49.6)

223 (49.9)

368 (51.2)

CC

122 (34.3)

91 (32.3)

137 (30.6)

244 (34.0)

OR (95% CI)**

1.09 (0.78–1.52)

0.85 (0.66–1.10)

P value

0.65

0.25