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The HUGO Journal

Official Journal of the Human Genome Organisation

Fig. 2 | Genomic Medicine

Fig. 2

From: Transcriptional activity of the RHOB gene is influenced by regulatory polymorphisms in its promoter region

Fig. 2

Functional analysis of the VNTR sequence within the RHOB promoter. (a) Influence of different TR numbers on the transcriptional activity of the RHOB gene in SW1353 cells (a) and in HeLa cells (b). RHOB wildtype-haplotype promoter sequences including 9 (pGL3-9TR) or 13 TRs (pGL3-13TR) were cloned into the pGL3-enhancer vector. Each experiment was performed six times; relative luciferase units are given as mean ± SD

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