Identification of gene biomarkers for respiratory syncytial virus infection in a bronchial epithelial cell line

The HUGO Journal

Official Journal of the Human Genome Organisation

Table 3 Genes in P53 signaling pathway that were differentially expressed at 24 h (24 H) after RSV infection. Fold changes at 4 h (4 H) are also shown

UniGene	Symbol	Fold		Gene name
UniGene	Symbol	4 H	24 H	Gene name
Hs.446564	DDB2	1.39	7.50	Damage-specific DNA binding protein 2, 48 kDa
Hs.567303	MDM2	−1.07	4.74	MDM2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)
Hs.469543	SESN2	1.32	3.13	Sestrin 2
Hs.467020	BBC3	1.44	3.02	BCL2 binding component 3
Hs.110571	GADD45B	1.18	2.76	Growth arrest and DNA-damage-inducible, beta
Hs.96	PMAIP1	−1.04	2.61	Phorbol-12-myristate-13-acetate-induced protein 1
Hs.500466	PTEN	1.06	2.11	Phosphatase and tensin homolog (mutated in multiple advanced cancers 1)
Hs.370771	CDKN1A	1.04	2.07	Cyclin-dependent kinase inhibitor 1A (p21, CIP1)
Hs.295923	SIAH1	−1.55	2.02	Seven in absentia homolog 1 (Drosophila)
Hs.558304	CASP8	−1.58	−2.63	Caspase 8, apoptosis-related cysteine peptidase
Hs.24529	CHEK1	−1.05	−2.86	CHK1 checkpoint homolog (s. Pombe)
Hs.567387	CCNE2	−1.39	−4.00	Cyclin E2