Skip to main content

Advertisement

Official Journal of the Human Genome Organisation

The HUGO Journal Cover Image

Table 2 Analysis of the association of SNP with cancer susceptibility under a recessive model of inheritance in the combined Swedish and Finnish samples

From: Germ-line variation at a functional p53 binding site increases susceptibility to breast cancer development

Sample Size Genotype Freq (%) OR (95% CI) P value
GG or GT TT
Controls 2,739 97.08 2.92   
All cases 3,512 96.07 3.93 1.34 (1.01, 1.77) 0.04
ER+ cases 2,492 96.27 3.73 1.26 (0.92, 1.72) 0.15
ER− cases 588 95.58 4.42 1.48 (0.93, 2.35) 0.10
Postmenopausal cases 2,447 96.24 3.76 1.30 (0.96, 1.76) 0.10
Premenopausal cases 502 94.82 5.18 1.66 (1.00, 2.75) 0.05
Sporadic cases 2,359 96.31 3.69 1.25 (0.92, 1.70) 0.16
Familial cases 1,098 95.72 4.28 1.48 (1.01, 2.17) 0.04