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The HUGO Journal

Official Journal of the Human Genome Organisation

Fig. 1 | The HUGO Journal

Fig. 1

From: Current status and future potential of somatic mutation testing from circulating free DNA in patients with solid tumours

Fig. 1

Harvesting tumour derived DNA. Circulating free DNA could represent genetic profile of the tumour better than DNA from biopsy. A primary tumour could contain many subclones of tumour cells, which have different genetic profiles, and as biopsy material is usually obtained from only one small part of the tumour, it might not contain materials from all the subclones (adapted from Fleishhacker et al. 2008)

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