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Official Journal of the Human Genome Organisation

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Table 3 Comparison of current data with earlier study

From: The use of race, ethnicity and ancestry in human genetic research

  Sankar et al. (2007) Current study
Data derived from articles from publication years 2001–2004 2008–2009
# Articles 330 170
Sample selection criteria Medline search strategy: race and ethnicity, genetics and population keywords; AND publication in one of 3 journal type samples (genetics, clinical, and general); mainly high impact journals Pubmed search strategy: (race OR ethnicity OR ancestry) AND (SNP OR polymorphism OR CNV) keywords; AND publication in one of six leading journals for the publication of human genetic research; mainly high impact journals
Variables coded
Basic features P value by chi sq
 Hypothesis 99 (30%) 169 (99.4%) <0.001*
 Limitations 75 (22.70%) 87 (52.4%) <0.001*
 Sample origin 206 (62.40%) 163 (95.9%) <0.001*
Reason for using populations
 Why populations 36 (10.90%) 113 (66.5%) <0.001*
 Why this population 37 (11.20%) 116 (68.2%) <0.001*
 Defines generic ‘race and ethnicity’ or ‘ancestry’ 0%  0% N/A
Ways of using populations in research
 Label for study population only 76 (23%) 82 (48.2%) <0.001*
 Independent variable 154 (46.70%) 87 (51.2%) 0.389
 Dependent variable 16 (4.80%) 1 (0.59%) 0.026*
 DNA with a label 35 (10.60%)  23 (13.5%) 0.412
  1. * Indicates statistically significant difference, P < 0.05