Table 1 Genes overrepresented in Cell Cycle, PI3K/AKT, apoptosis and death receptor signaling canonical pathways. Expression level are shown as Log10 values

Cell cycle controlling genes

    Cyclin D3

M92287

3.22

BNT

    CDK2

M68520

3.02

3.60

    CDC25A

M81933

2.20

3.43

    TP53

M14694

3.30

3.70

    Cyclin D1

X59798

3.54

3.93

    E2F-1

M96577

3.34

3.84

    RB1

M15400

3.50

4.18

    CDK4

M14505

3.37

4.50

    CDC2

X05360

3.31

4.65

    Cyclin B1

M25753

3.69

5.02

    Cyclin D2

D13639

BNT

BNT

    CDC25C

M34065

BNT

3.35

    APC

M74088

BNT

3.44

PI3K/AKT signaling

    AXL

M76125

2.42

BNT

    ITGA2

M28249

2.20

BNT

    PTK7

U33635

3.88

BNT

    TIE1

X60957

1.47

BNT

    AKT1

M63167

3.17

BNT

    AKT2

M77198

BNT

3.16

    FRAP1

L34075

BNT

1.63

    ILK

U40282

BNT

3.66

    PPP2R5E

L76703

BNT

3.01

    JAK2

AF005216

BNT

3.58

    RELB

M83221

BNT

3.90

    MAP3K5

D84476

BNT

3.67

    NFKB2

X61498

BNT

3.57

    SFN

AF029082

BNT

3.48

    NFKBIA

M69043

BNT

3.86

    FGFR1

M37722

BNT

3.34

    MAPK3

X60188

BNT

3.58

    EGFR

X00588

BNT

3.73

    PPP2R5B

L42374

BNT

2.62

    PPP2R5A

L42373

BNT

4.22

    TYRO3

D17517

BNT

3.81

    ERBB4

L07868

BNT

2.65

    PDGFRA

M21574

BNT

3.27

    PTEN

U92436

BNT

4.08

    MAP2K2

L11285

BNT

3.61

    NRAS

X02751

BNT

4.20

Apoptosis

    MAP3K14

Y10256

3.72

BNT

    MAP2K7

AF022805

2.91

BNT

    CASP8

U60520

2.83

BNT

    CASP7

U37448

BNT

2.68

    ROCK1

U43195

BNT

3.28

    PARP1

M18112

BNT

3.81

    TNFRSF1A

M33294

BNT

3.14

    BAK1

U23765

BNT

3.38

    FAS

Z70519

BNT

3.14

    BAX

L22474

BNT

3.45

    APAF1

AF013263

BNT

2.96

    CASP2

U13021

BNT

4.07

Death receptor signaling

    TNFRSF25

Y09392

3.67

BNT

    CRADD

U84388

3.34

BNT

    CFLAR

AF010127

BNT

2.39

    TNFRSF10B

AF016268

BNT

1.92