Official Journal of the Human Genome Organisation
Table 3 Genomic diseases resulting from recurrent genomic rearrangements
Rearrangement | Type | Recombination substrates | |||
|---|---|---|---|---|---|
Repeat size | Identity (%) | Orientation | Type | ||
Inv dup(15)(q11q13) | Inverted dup | >500 | Â | C | Â |
Inv dup(22)(q11.2) | Inverted dup | ~225–400 | 97–98 | C |  |
Idic(X)(p11.2) | Isodicentric | Â | Â | I? | Â |
Inv dup(8)(pterp23.1::p23.2pter); Del(8)(p23.1p23.2) | inv/dup/del | ~400 | 95–97 | I | Olfactory receptor gene cluster |
dup(15)(q24q26) | dup | ~13–60 |  | ? |  |