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Official Journal of the Human Genome Organisation

Table 3 The distribution of renal function for each treatment arm for the subgroups of DD, ID and II patients

From: High dose Losartan and ACE gene polymorphism in IgA nephritis

Patients

Renal function

Treatment group

P-value *

 

High dose ARB

Normal dose ARB

ACEI 20 mg

ACEI 10 mg

DD

Improved

4 (66.67%)

0 (0%)

2 (15.38%)

2 (33.33%)

0.183

Stable

2 (33.33%)

4 (80%)

8 (61.54%)

3 (50%)

ESRF

0 (0%)

1 (20%)

3 (23.08%)

1 (16.67%)

Total

6 (100%)

5 (100%)

13

6

ID

Improved

8 (40%)

5 (31.25%)

1 (4.55%)

1 (5.56%)

0.008

Stable

10 (50%)

8 (50%)

13 (59.09%)

14 (77.78%)

ESRF

2 (10%)

3 (18.75%)

8 (36.36%)

3 (16.67%)

Total

20 (100%)

16 (100%)

22 (100%)

18 (100%)

II

Improved

11 (31.43%)

4 (16.67%)

3 (10.34%)

0 (0%)

0.012

Stable

17 (48.57%)

14 (58.33%)

18 (62.07%)

8 (61.54%)

ESRF

7 (20%)

6 (25%)

8 (27.59%)

5 (38.46%)

Total

35 (100%)

24 (100%)

29 (100%)

13 (100%)

  1. The table shows the no. of patients (% of patients) with improved, stable renal function and ESRF
  2. P-value are from Chi-square test for trend