Genetic determinants of immune-response to a polysaccharide vaccine for typhoid

The HUGO Journal

Official Journal of the Human Genome Organisation

Table 5 List of 54 SNPs in 43 genes, along with the corresponding correlation coefficient between minor allele frequency and antibody response, that showed significant association with antibody response in half-sample 1

Chromosome no.	Gene	SNP rs #	Corr. coeff. (r)	Chromosome no.	Gene	SNP rs #	Corr. coeff. (r)
1	TNFRSF8	12736809	−0.94	4	IRF2	12512614	−0.96
1	TNFRSF1B	505844	−0.97	6	BAT2	2736172	−0.91
1	IL12RB2	7555183	−0.99	6	HLA-DOB	2859579	−0.99
1	TGFBR3	1017956	−0.94	6	IL22RA2	13197049	0.92
1	XCL1	6700487	0.91	6	CCR6	1571878	−0.96
1	PTGS2	2745557	0.93	8	DEFB1	2978873	0.98
1	IRF6	2073486	−0.93	8	DEFB1	2977772	0.91
1	NLRP3	12565738	−0.92	8	IKBKB	3747811	−0.95
1	NLRP3	10754558	0.98	9	PAX5	7031673	−0.91
2	IL1R2	13022757	−0.93	10	IL2RA	10905668	0.98
2	IL1R2	4850993	−0.95	10	ITGB1	10827164	−0.95
2	IL1R2	3218848	0.98	10	CXCL12	10900030	0.96
2	IL1R2	2110562	−0.92	10	MAPK8	12358297	−0.95
2	IL1RL1	10208293	0.95	10	CHUK	2230804	−0.91
2	IL18R1	1362348	0.92	11	CD59	3181274	−0.94
2	CTLA4	231779	−0.99	11	CD44	112762	−0.97
3	IL5RA	2290610	−0.98	11	IL10RA	4252306	0.93
3	CMTM8	4132830	−0.96	11	TIRAP	8177352	0.98
3	CMTM7	17029530	−0.97	13	IL17D	1888001	0.94
3	CD80	491407	−1.00	13	TNFRSF19	7338328	−0.98
3	CD80	2228017	−0.97	16	IL4R	4787423	0.96
3	CD80	2222631	−0.93	17	CSF3	2227321	−0.95
3	CD80	16829988	−0.99	17	MAP2K6	12946388	−0.95
3	CD86	2681411	0.97	21	ITGB2	235326	0.99
3	CD86	17203439	0.95	22	MAPK1	743409	−0.93
4	TLR1	5743572	0.93	22	MAPK1	2283792	−0.98
4	CXCL13	171388	−0.94	22	MAPK1	3788332	−0.94