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The HUGO Journal

Official Journal of the Human Genome Organisation

Fig. 4 | The HUGO Journal

Fig. 4

From: Genome-wide identification and annotation of HIF-1α binding sites in two cell lines using massively parallel sequencing

Fig. 4

Fold change in the amount of RNA present in polysome fractions in response to hypoxic stimuli. Distributions of the fold changes of transcripts in the polysome fractions in response to hypoxia, as determined by digital RNA-Seq tag counts. Fold changes in HIF-1α-bound target genes for which transcriptional induction was observed (left), HIF-1α-bound genes for which no transcriptional induction was observed (middle) and all RefSeq genes (right) are shown. Statistical significance in the differences in the distributions were evaluated using the Wilcoxon rank sum test and are shown in the margin

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