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Official Journal of the Human Genome Organisation

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Archived Comments for: The extent of functionality in the human genome

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  1. Larry Moran's critique

    Martin Hafner, Institute for Genetics, University of Cologne

    19 December 2013

    Readers may be interested in Larry Moran's critique at his Sandwalk blog (

    IMO T. Ryan Gregory's onon test cited by Mattick is not so much about the fact that onion genomes are bigger than the human genome but rather about the fact that the sizes of the smallest and the biggest onion genomes differ by a factor of 5. One would have to claim different complexities for these onion species if one beleaves that most sequences are functional.

    Competing interests

    None declared